Enzymes

ENZYMES

Submitted to:

Dr. Gul Shahnaz

Submitted by:

Group 1 A
Adeel Afzal
Fatima Saleh
Fatima Zahid
Maida Shafiq
Najia Hafeez

CONTENTS

Chemistry
Classification
Mechanism of Enzyme Action
Enzyme Kinetics
Inhibition
Activation
Specificity

CHEMISTRY

Introduction

 Enzymes are biological catalysts that speed up the rate of the biochemical reaction.

 Most enzymes are three dimensional globular proteins (tertiary and quaternary structure).

 Some special RNA species also act as enzymes and are called Ribozymes e.g. hammerhead ribozyme.

STRUCTURE OF ENZYMES

 The active site of an enzyme is the region that binds substrates, co-factors and prosthetic groups and contains residue that helps to hold the substrate.

 Active sites generally occupy less than 5% of the total surface area of enzyme.

 Active site has a specific shape due to tertiary structure of protein.

 A change in the shape of protein affects the shape of active site and function of the enzyme.


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