Principles and Practice of Cleaning in Place ( Graham Broadhurst )

Contents

CIP/SIP – Definitions / Function

Principles of CIP

CIP Detergents

CIP Systems

Vessel CIP

Mains CIP

Monitoring/Control

CIP / SIP – Definition

CIP = Cleaning in Place

To clean the product contact surfaces of vessels, equipment and pipework in place. i.e. without dismantling.

SIP = Sterilise in Place

To ensure product contact surfaces are sufficiently sterile to minimise product infection.

How CIP Works

Mechanical

Removes ‘loose’ soil by Impact / Turbulence

Chemical

Breaks up and removes remaining soil by Chemical action

Sterilant/Sanitiser

‘Kills’ remaining micro-organisms (to an acceptable level)

Factors affecting CIP

Mechanical

Chemical

Temperature

Time

CIP Operation

PRE-RINSE

– Mechanical Removal of Soil

DETERGENT

– Cleaning of Remaining Soil

– Caustic, Acid or Both

FINAL RINSE

– Wash Residual Detergent/Soil

STERILANT/SANITISER

– Cold or Hot


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