Etiket Arşivleri: PROBIOTICS

Probiyotikler ve Kullanım Alanları ( Başar UYMAZ )

Probiyotikler ve Kullanım Alanları
Probiotics and Their Use

ÖZET

Gıdaların üretiminde tüketici sağlığını destekleyici ve immün sistemi uyaran etkilere sahip mikroorganizmaların kullanımı giderek artmaktadır. Bu mikroorganizmaların önemli bir grubunu teşkil eden probiyotiklerin gastrointestinal sistem hastalıklarının engellenmesi ve tedavisinde ve normal mikrofloranın oluşumunda önemli bir rol oynadığı klinik denemelerle belirlenmiştir. Diğer yandan probiyotiklerin, suştan suşa farklılık gösteren gıda koruyucu etkileri ve değişik hastalıkların tedavisinde kullanım potansiyelleri üzerinde çalışmalar devam etmektedir. Özellikle çocuklarda görülen akut diyare ve antibiyotik kullanımına bağlı diyarenin tedavisinde etkin kullanım potansiyeli taşıyan probiyotik preparatları geliştirilmiştir. Bu derleme makalesinde probiyotik suşların seçiminde kullanılan karakteristikler, kullanım olanakları ve tedavi edici potansiyelleri, güncel bilgiler taranarak verilmiştir.

Anahtar Kelimeler : Probiyotik, Gastrointestinal sistem, Gıda güvenliği, Tedavi.

ABSTRACT

There is increasing demand to use the microorganisms, supporting consumer health and stimulating immune system, in food production. The role of probiotics which are one of the most important group of this microorganisms on the preventation of gastrointestinal diseases and treatment and development of normal gastrointestinal flora were determinated by clinical trials. On the other hand, studies on the strain-dependent food preservation effects and the potentials for treatment of different diseases of probiotics are ongoing. Probiotic preparats that have effective potential especially for the treatment acute diarrhea in children and antibiotic associated diarrhea have been developed. In this review, newsworthy information on the criteria for probiotic strain selection, curing potentials and their application possibilities were presented.

Keywords : Probiotics, Gastrointestinal system, Food safety, Treatment.


Kaynak: http://pajes.pau.edu.tr/Archive/PAJES_16_1_95_104.pdf

Probiotics

PROBIOTICS

Definition

Live microbial feed supplements that have beneficial effects on the host by improving its intestinal microbial balance.

HISTORY

Elie Metchnikoff

At the start of the 20th century, Russian noble prize winner and father of modern immunology, Elie Metchnikoff, a scientist at the Pasteur institute, was the first conceptualize “probiotics”.

In 1907 Metchnokoff proposed that the acid producing bacteria in fermented milk products could prevent “fouling” in the large intestine and if consumed regularly, lead to a longer, healthier life

In early 1930’s, in Japan, Minoru shirota developed a fermented milk product called Yakult (probiotic yogurt like product made by fermenting a mixture of skimmed milk with a special strain of Lactobacillus casei shirota).

Probiotic term coined in 1965 by Lilly and Stillwell.

Newborn Microbiota

Initially depends on

Mother’s microbiota maternal vaginal and intestinal flora constitutes the source of bacteria, which colonizes the intestine of new born.

Mode of deliver

Birth environment

Rarely genetic factors

After infantry probiotics supplied from raw foods; such as lactic acid fermented foods such as yogurt, cheese and probiotic supplements.

Factors affecting the intestinal micro ecosystem

Antibiotics and other drug intake
Microbial infections
Diet (highly processed, low fiber foods)
Chronic diarrhea
Stress
Chlorinated water
Radiation and chemotherapy
Colonic therapies for detoxification

Characteristics of Effective Probiotics

Able to survive the passage through the digestive system.
Able to attach to the intestinal epithelia and colonise.
Able to maintain good viability.
Able to utilise the nutrients and substrates in a normal diet. non pathogenic and non toxic.
Capable of exerting a benificial effect on the host.
Stability of desired characteristics during processing, storage and transportation.
Anti-inflammatory, antimutagenic, immunostimulatory.