Etiket Arşivleri: Flavonoids

Fonksiyonel Besinlerin Sağlığımız Üzerine Etkileri ( Prof. Dr. Turgay COŞKUN )

Fonksiyonel besinlerin sağlığımız üzerine etkileri
Turgay Coşkun
Hacettepe Üniversitesi Tıp Fakültesi Pediatri Profesörü


Developing scientific technology has increased our awareness of the relationship between diet and disease, and there has been a growing interest in functional foods and their role in the maintenance and improvement of health and wellness. Foods can no longer be evaluated only in terms of macro- and micronutrient content alone. Recently, more attention is being paid to the role of food in bioregulating functions. Any food that exerts health properties beyond the traditional nutrients it contains is termed a functional food. They can be whole, fortified, enriched or genetically engineered foods that are consumed as a part of a daily regular diet. A variety of functional foods or food ingredients have been shown to improve health, reduce the risk of chronic diseases and have an impact on the prevention and treatment of various diseases. Many different fruits, vegetables, grains, fish, and dairy and meat products contain several components that deliver health benefits beyond basic nutrition, such as lycopene in tomatoes, omega-3 fatty acids in salmon and phytoestrogens in soy. Regular consumption of functional foods can help reduce the risk of or manage a number of health concerns, including cancer, cardiovascular disease, gastrointestinal health, menopausal symptoms, osteoporosis and eye health. It should be born in mind that functional foods are not magic bullets and that they are for the establishment of good health. The most effective way to reap the health benefits from foods is to eat a balanced and varied diet.

Key words: functional foods, health, nutraceuticals, phytochemicals, phytoestrogens, flavonoids, polyphenols, phytosterols, omega-3 fatty acids, conjugated linoleic acid,
prebiotics, probiotics, synbiotics.


Bilimsel teknolojideki gelişmeler diyet ve hastalıklar arasındaki ilişkiyi anlamamıza olanak vermiş olup, fonksiyonel besinle, bunların sağlığımızın korunması ve geliştirilmesindeki rolleri daha çok ilgi çeker hale gelmiştir. Besinler artık sadece içerdikleri makro- ve mikrobesleyiciler ile değerlendirilmez olmuştur. Son zamanlarda biyolojik düzenleyici rolleri üzerinde daha çok durulmaktadır. Temel besleyici özelliklerinin ötesinde sağlığımıza olumlu katkıları olan besinlere fonksiyonel besinler adı verilmektedir. Fonksiyonel besinler hiçbir işlem görmemiş doğal bir besin maddesi olabileceği gibi fonksiyonel bir besin öğesi ile zenginleştirilmiş veya genetik mühendislik yöntemleri ile değişikliğe uğramış bir besin de olabilir ve günlük diyetle tüketilir. Çok çeşitli besin ve besin ögesinin sağlığımız üzerinde olumlu etkileri, bazı kronik hastalıklardan korunmada ve bu hastalıkların tedavisinde katkıları olduğu gösterilmiştir. Domateste bulunan likopen, somon balığında bulunan omega-3 yağ asitleri ve soyada bulunan fitoöstrojenler gibi çeşitli meyva ve sebzelerle tahıllar, balık, süt ve et ürünlerinde fonksiyonel özellikli bileşenler bulunmaktadır. Düzenli fonksiyonel besin tüketimi kanser ve kardiyovasküler hastalıklardan korunma ve tedavide, gastrointestinal sistemin sağlığının korunmasında, menapoz semptomlarının hafifletilmesi, osteoporozun önlenmesi ve göz salığının korunmasında etkilidir. Fonksiyonel besinlerin sihirli birer mermi oldukları düşünülmemeli, sağlığımız üzerindeki olumlu etkilerinden yararlanabilmek için çeşitli besinleri içeren dengeli bir diyet tüketmeliyiz.

Anahtar kelimeler: fonksiyonel besinler, sağlık, nutrasötikler, fitokimyasallar, fitoöstrojenler, flavonoidler, polifenoller, fitosteroller, omega-3 yağ asitleri, konjuge linoleik asit, prebiyotikler, probiyotikler, sinbiyotikler.

Flavonoids ( Dr. Louay Labban )


Dr. Louay Labban

A’Sharqiyah University


• Polyphenolic compounds that are ubiquitous in nature and are categorized, according to chemical structure, into flavonols, flavones, flavanones, isoflavones, catechins, anthocyanidins and chalcones

What are flavonols?

• Flavonols are phytochemical compounds found in high concentrations in a variety of plant-based foods and beverages. Based on their structure, flavonols are classified as flavonoids and include the following compounds: quercitin, kaempferol, and myricetin.

• Over 4,000 flavonoids have been identified, many of which occur in fruits, vegetables and beverages (tea, coffee, beer, wine and fruit drinks).

• The flavonoids have aroused considerable interest recently because of their potential beneficial effects on human health they have been reported to have antiviral, antiallergic, antiplatelet, antiinflammatory, antitumor and antioxidant activities.

• Antioxidants are compounds that protect cells against the damaging effects of reactive oxygen species, such as singlet oxygen, superoxide, peroxyl radicals, hydroxyl radicals and peroxynitrite.

An imbalance between antioxidants and reactive oxygen species results in oxidative stress, leading to cellular damage. Oxidative stress has been linked to cancer, aging, atherosclerosis, ischemic injury, inflammation and neurodegenerative diseases (Parkinson’s and Alzheimer’s).

• Flavonoids may help provide protection against these diseases by contributing, along with antioxidant vitamins and enzymes, to the total antioxidant defense system of the human body.

• Epidemiological studies have shown that flavonoid intake is inversely related to mortality from coronary heart disease and to the incidence of heart attacks.

• The recognized dietary antioxidants are vitamin C, vitamin E, selenium, and carotenoids. However, recent studies have demonstrated that flavonoids found in fruits and vegetables may also act as antioxidants.